Peking University core, science and technology core papers published, SCI published.
Macrophyte, non nervous system embolism, mitral valve involvement, Staphylococcus aureus infection and uncontrolled infection are independent risk factors of NC.
Results Among 448 subjects, 234 had dyslipidemia, accounting for 52.23% of the total population.
156 patients (50.6%) underwent valve surgery, which significantly reduced IE related deaths for 1 year (HR=0.160,95% CI 0.063-0.405, P< 0.001).
For IE patients with NC, valve surgery is relatively safe and may improve the prognosis of specific patients.
The changes of plasma Lp-PLA2 and sPLA2 levels in newly diagnosed T2DM patients after CSII treatment are related to the improvement of insulin resistance, which may play a protective role in diabetes macroangiopathy.
The 25 (OH) D level was compared between the two groups according to whether there was abnormal blood lipid; The blood lipid levels of each group were compared according to 25 (OH) D quartile; The risk factors of dyslipidemia were analyzed by logistic regression.
After treatment, sPLA2 decreased significantly compared with that before treatment [173.78 (80.95,278.09) μ G/L ratio 219.33 (130.03337.30) μ g/L，P< 0.01], while the level of Lp PLA2 was not significantly reduced [88.35 (76.74125.18) μ G/L ratio 102.9 (76.34134.31) μ g/L，P> 0.05], but the changes of both levels before and after treatment were positively correlated with the changes of HOMA-IR assessed by the homeostasis model (r values were 0.537 and 0.493, respectively, P< 0.05).
NC was independently associated with poor long-term prognosis (HR=2.292, 95% CI 1.274-4.122, P=0.006).
Methods The clinical data, NC, treatment and prognosis of patients with left ventricular IE admitted from 2001 to 2012 were analyzed.
Conclusion NC is associated with poor prognosis of IE.
In NC group, hospitalization and 1-year IE related mortality of patients undergoing valve surgery were also significantly reduced (14.8% vs 5.3%, 18.5% vs 73.7%, respectively, P< 0.001).
Clinical trial registration China Clinical Trial Registration Center, ChiCTR － TRC － 10001618.
The level of 25 (OH) D in the total population and people of different sexes with dyslipidemia was significantly lower than that in the normal blood lipid group, P; 0.05。 Our 25 (OH) D level is 15.7 (12.2, 20.1) μ G/L, of which 91.1% were not sufficient in vitamin D.
It covers a wide range of disciplines, and is included in four major searches: Knowledgeable, Wanfang, Weipu and Longyuan.
Objective To investigate the risk factors of nervous system complications (NC) in left ventricular infective endocarditis (IE) and its influence on cardiac surgery and prognosis.
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Methods A cross-sectional survey was conducted in 448 middle-aged and elderly people in a community in Beijing.
65 patients (21.1%) had NC.
During the follow-up period (median time 17 months), 70 cases (22.7%) died.
Through the multidisciplinary cooperation of 10 specialties including emergency, critical care, digestion, obstetrics, endocrinology, ultrasound, radiation, infection, nutrition and surgery, the patient finally improved.
According to the 25 (OH) D quartile, the prevalence of dyslipidemia increased with the decrease of 25 (OH) D level; TC, TG and LDL-C increased, HDL-C decreased; After adjusting for age, sex and other factors, logistic regression results showed that the risk of dyslipidemia in the lowest quartile of 25 (OH) D was 143% higher than that in the highest quartile..
To investigate the effect of short-term intensive insulin therapy on plasma levels of lipoprotein associated phospholipase A2 (Lp-PLA2) and secretory phospholipase A2 (sPLA2) in newly diagnosed type 2 diabetes patients and its clinical significance.
General data, biochemical, blood lipid and 25 (OH) D indexes were collected.
Macrophyte (HR=1.681, 95% CI 1.013 ～ 2.788, P=0.044), non nervous system embolism (HR=1.820, 95% CI 1.068 ～ 3.100, P=0.028), mitral valve involvement (HR=1.888, 95% CI 1.089 ～ 3.274, P=0.024), Staphylococcus aureus infection (HR=2.054, 95% CI 1.097 ～ 3.846, P=0.024) and uncontrolled infection (HR=4.680, 95% CI 2.563 ～ 8.546, P< 0.001) were independent risk factors for NC.
A 32 year old late pregnancy patient with severe acute pancreatitis induced by hypertriglyceridemia caused multiple organ failure, pancreatic necrosis and infection, abdominal compartment syndrome and fetal death in utero.
90 newly diagnosed T2DM patients received continuous subcutaneous insulin infusion (CSII) with insulin pump for 2 weeks.
Objective To investigate the nutritional status of serum vitamin D in middle-aged and elderly people in Beijing, and to explore the correlation between 25 hydroxyvitamin D [25 (OH) D] and dyslipidemia.
Results A total of 308 patients, aged (45.3 ± 15.9) years, were enrolled.
